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CEPI 2.0 Mid Term Review
webCredibility Rating
4/5
High(4)High quality. Established institution or organization with editorial oversight and accountability.
Rating inherited from publication venue: CEPI
This document is primarily relevant to biosecurity and pandemic preparedness tracking rather than core AI safety; it may be tangentially useful for those studying global catastrophic biological risk governance and international coordination mechanisms analogous to AI governance challenges.
Metadata
Importance: 30/100organizational reportanalysis
Summary
This is the mid-term review of CEPI 2.0 (Coalition for Epidemic Preparedness Innovations), assessing progress toward its strategic goals of developing vaccines against epidemic and pandemic threats within 100 days. The review evaluates organizational effectiveness, funding use, and scientific progress in pandemic preparedness infrastructure. It includes a management response outlining how CEPI plans to address identified gaps and recommendations.
Key Points
- •Reviews CEPI 2.0's strategic plan progress, including the ambitious 100-Days Mission to develop safe, effective vaccines rapidly in response to future pandemic threats.
- •Assesses organizational performance, governance structures, and deployment of resources across CEPI's vaccine development portfolio.
- •Identifies gaps and challenges in pandemic preparedness, with management responses outlining corrective actions and strategic adjustments.
- •Relevant to biosecurity and global health security communities tracking international coordination mechanisms for pandemic risk reduction.
- •Published February 2025, providing timely insight into the state of global biological risk preparedness infrastructure.
Cited by 1 page
| Page | Type | Quality |
|---|---|---|
| Coalition for Epidemic Preparedness Innovations | Organization | 53.0 |
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Management Response
Mid-term Review of CEPI 2.0 Strategy
Evaluation Title:
CEPI 2.0 Mid-term Review Final Report
Evaluation Completion Date: September 2024
Publication Date: February 2025
Purpose and scope of the evaluation: At the beginning of 2024, the Coalition for Epidemic Preparedness
Innovations (CEPI) commissioned Itad and Market Access Africa (MAA) to conduct an independent
Midterm Review (MTR) of CEPI 2.0. The primary objective of this review is to assess progress against
CEPI’s 2.0 Strategy at its midpoint. Launched in 2022, CEPI’s five-year strategic plan aims to prepare,
transform, and connect the world to effectively respond to the next Disease X by compressing vaccine
development timelines to as little as 100 days after the identification of a novel virus. This MTR had two
main goals: 1) to assess the relevance, coherence, fidelity, effectiveness, impact, governance, and
management of CEPI’s operational model and strategy; and 2) to identify lessons learned, capture good
practices, and generate recommendations that will inform and strengthen the implementation of the
remaining period of CEPI 2.0.
I. Overall Management Response
CEPI welcomes the insights and recommendations from the Mid-term Review (MTR). Since its
inception CEPI has placed learning, evolving and striving to do better at the heart of its culture, so
independent, external assessments are a necessary and useful tool for us as an organisation, and for
our Board and Investors. We would like to express our gratitude to the evaluation team, Itad and Market
Access Africa, for delivering an insightful and thought-provoking report. We also wish to thank the
Independent Evaluation Committee and its Chair for their leadership and expertise in ensuring CEPI
receives a high-quality, actionable report.
The MTR was conducted halfway through CEPI’s second five-year funding cycle (2022-2026), and
seven years into CEPI’s existence. It provides an important opportunity for CEPI to take stock of
progress against the CEPI 2.0 strategy and identify areas where the organisation needs to sharpen its
focus or course correct to achieve its aims, building on previous evaluations including the 2023 Board
effectiveness review and the independent assessment of CEPI 1.0. Conducting the MTR at this stage was
intentional: the insights it provides will contribute meaningfully to ongoing discussions around the
CEPI 2.0 timeline, expected deliverables, and any needed adjustments of focus or direction. They will
also help lay the foundation for CEPI’s next strategic phase and the development of plans for CEPI 3.0.
Key Insights from the MTR
CEPI 2.0 is an ambitious strategy, conceived in 2021 at the height of the COVID-19 pandemic. It built on
CEPI’s learnings in 1.0 and COVID-19, carried programmes initiated during these phases forward, and
added new areas of focus. The MTR recognizes the significant ambition of CEPI 2.0 and acknowledges
that there will be delays in achieving some goals. It also
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