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Biosecurity resources
webCredibility Rating
4/5
High(4)High quality. Established institution or organization with editorial oversight and accountability.
Rating inherited from publication venue: Nuclear Threat Initiative
NTI is a leading policy organization on nuclear and biological threats; this hub is relevant to AI safety due to its focus on AI-bio convergence risks and governance gaps in AI models used in life sciences.
Metadata
Importance: 52/100homepage
Summary
The Nuclear Threat Initiative (NTI) biosecurity program addresses biological threats from natural, accidental, and intentional sources, including the intersection of AI and biotechnology. It advances global health security through policy advocacy, governance frameworks, and international coordination to prevent biological catastrophe.
Key Points
- •Less than 3% of biological AI models have safeguards to reduce risks of misuse, highlighting a major governance gap.
- •The Global Health Security Index shows average preparedness score of 38.9/100, with 178 countries scoring under 50 for biosecurity systems.
- •NTI runs the AIxBio Global Forum to develop international governance at the convergence of AI and life sciences.
- •Technological advances are lowering barriers for malicious actors to misuse biology, increasing catastrophic risk.
- •Programs span biotechnology governance, biological weapons reduction, health security, and next-generation biosecurity leadership.
Cited by 1 page
| Page | Type | Quality |
|---|---|---|
| Bioweapons Risk | Risk | 91.0 |
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# Biological
The dangers are real.
We can build a safer world.
NTI offers solutions.

## The risks are clear.
* * *
### Biological threats—natural, intentional, or accidental—could kill millions and cost trillions.
COVID-19 demonstrated how rapidly a biological crisis can spread in today’s interconnected world. Political instability, urbanization, and climate change further complicate the challenge. Technological advances are lowering the barriers to entry and amplifying the potential harm that a malicious actor can cause with biology.

<3% Percentage of biological AI models with safeguards to reduce risks of misuse.
38.9 The average 2021 GHS Index score out of 100, showing that global preparedness for epidemics and pandemics is fundamentally weak.
178 The number of countries with a score of less than 50 out of 100 for biosecurity systems to prevent deliberate biological events.
## We can build a safer world.
* * *
### Biological threats are growing. All countries must prepare to prevent and respond.
Governments, NGOs, academia, and the private sector share the responsibility to strengthen international capabilities to prevent global biological catastrophe.
To advance this important goal, NTI \| bio fosters new thinking, tests solutions, and advocates for systemic change.
Here's what we're doing
- [Strengthening biotechnology governance](https://www.nti.org/area/biological/strengthening-biotechnology-governance/)
- [Improving biosecurity in countries around the world](https://www.nti.org/area/biological/improving-biosecurity-in-countries-around-the-world/)
- [Reducing the risk of biological weapons development and use](https://www.nti.org/about/programs-projects/project/reducing-state-biological-weapons-risks/)
- [Advancing global health security](https://www.nti.org/area/biological/advancing-global-health-security/)
- [Fostering the next generation of global biosecurity leaders](https://www.nti.org/about/programs-projects/project/next-generation-for-biosecurity/)
## Featured Projects
[AIxBio Global Forum](https://www.nti.org/about/programs-projects/project/aixbio-global-forum/)
#### AIxBio Global Forum
Facilitating international governance to reduce biosecurity risks at the convergence of AI and the life sciences.
[Africa Health Security Index](https://www.nti.org/about/programs-projects/project/africa-health-security-index/)
#### Africa Health Security Index
Improving epidemic and pandemic preparedness and strengthening biosecurity in Africa.
[Biosecurity Innovation and Risk Reduction Initiative](https://www.nti.org/about/programs-projects/project/fostering-biosecurity-innovation-and-risk-reduction/)
#### Biosecurity Innovation and Risk Reduction Initiative
Advances in biotechnology outpace national governments’ ab
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