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Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases

paper

Authors

David Welch·Manuela Buonanno·Veljko Grilj·Igor Shuryak·Connor Crickmore·Alan W. Bigelow·Gerhard Randers-Pehrson·Gary W. Johnson·David J. Brenner

Credibility Rating

5/5
Gold(5)

Gold standard. Rigorous peer review, high editorial standards, and strong institutional reputation.

Rating inherited from publication venue: Nature

Scientific study on far-UVC light technology for pathogen inactivation; relevant to AI safety as biosecurity research addressing pandemic risks that could inform AI governance priorities and resource allocation in dual-use technology oversight.

Paper Details

Citations
1
Year
2017

Metadata

journal articleprimary source

Summary

This study demonstrates that far-UVC light (207-222 nm) can efficiently inactivate airborne viruses and bacteria without harming human skin or eyes, unlike conventional UVC light. The researchers show that a low dose of 2 mJ/cm² of 222-nm light inactivates over 95% of aerosolized H1N1 influenza virus. The key advantage of far-UVC is its strong absorbance in biological materials prevents penetration of human skin and eye tissue, while its wavelength is still short enough to penetrate and inactivate micrometer-sized or smaller pathogens. The authors propose continuous low-dose far-UVC light in indoor public spaces as a safe, inexpensive tool to reduce airborne disease transmission.

Cited by 1 page

PageTypeQuality
Bioweapons RiskRisk91.0

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Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases | Scientific Reports 
 
 
 

 

 

 
 
 
 

 

 
 
 
 
 
 

 
 
 
 
 
 

 
 

 
 
 
 
 
 
 
 
 
 
 

 
 

 

 

 
 

 
 
 

 
 

 
 
 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 

 
 
 

 
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 Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases
 
 
 
 
 
 
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 Subjects

 
 Antiviral agents 
 Influenza virus 

 
 

 
 
 
 
 
 
 
 
 
 
 
 
 
 An Author Correction to this article was published on 07 September 2021

 
 
 
 

 
 
 
 
 
 
 
 
 
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 Abstract

 Airborne-mediated microbial diseases such as influenza and tuberculosis represent major public health challenges. A direct approach to prevent airborne transmission is inactivation of airborne pathogens, and the airborne antimicrobial potential of UVC ultraviolet light has long been established; however, its widespread use in public settings is limited because conventional UVC light sources are both carcinogenic and cataractogenic. By contrast, we have previously shown that far-UVC light (207–222 nm) efficiently inactivates bacteria without harm to exposed mammalian skin. This is because, due to its strong absorbance in biological materials, far-UVC light cannot penetrate even the outer (non living) layers of human skin or eye; however, because bacteria and viruses are of micrometer or smaller dimensions, far-UVC can penetrate and inactivate them. We show for the first time that far-UVC efficiently inactivates airborne aerosolized viruses, with a very low dose of 2 mJ/cm 2 of 222-nm light inactivating >95% of aerosolized H1N1 influenza virus. Continuous very low dose-rate far-UVC light in indoor public locations is a promising, safe and inexpensive tool to reduce the spread of airborne-mediated microbial diseases.

 

 
 
 

 
 
 
 
 
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 Far-UVC (222 nm) efficiently inactivates an airborne pathogen in a room-sized chamber
 
 

 
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 Improved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a valida

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