University of Oxford — Malaria Vaccine Durability in School-Aged Children

[Global Health R&D] Open Philanthropy recommended a grant of $3,496,050 over three years to the University of Oxford to support a three-part study on the R21/Matrix-M malaria vaccine in school-aged children in Burkina Faso and Mali, led by Drs. Mehreen Datoo and Halidou Tinto. Part one of the study will examine the durability of the current four-dose vaccine schedule, as well as determine how much protection a school-age booster dose would provide. Parts two and three will evaluate the most suitable dose for a school-age booster, and the social acceptability of the school-age booster. This falls within our focus area of global health R&D.