Grant·I2hnMdQcu1·Record·Profile

Grant: Purdue University — Preclinical Data Research (Douglas Brubaker) (Coefficient Giving → Purdue University)

Verdictconfirmed95%

1 check · 4/3/2026

Deterministic match: grantee, amount, date matched in source snapshot (2714 rows)

Our claim

entire record

Grantee: Purdue University
Name: Purdue University — Preclinical Data Research (Douglas Brubaker)
Amount: $1,500,000
Currency: USD
Date: August 2021
Source: https://coefficientgiving.org/funds/
Notes: [Scientific Innovation: Tools and Techniques] Grant investigators: Heather Youngs and Chris Somerville This page was reviewed but not written by the grant investigators. Purdue University staff also reviewed this page prior to publication. Open Philanthropy recommended a gran… expand
[Scientific Innovation: Tools and Techniques] Grant investigators: Heather Youngs and Chris Somerville This page was reviewed but not written by the grant investigators. Purdue University staff also reviewed this page prior to publication. Open Philanthropy recommended a grant of $1,500,000 over five years to Purdue University to support research led by Dr. Douglas Brubaker on developing a computational model to translate preclinical data in mouse disease models to humans. It is not uncommon that preclinical data from mice fail to translate to similar preclinical results in humans, limiting the applicability of mouse data to human medicine. Dr. Brubaker intends to use this funding to develop a computational model that uses mouse data from an Alzheimer’s disease study conducted by Washington University to attempt to predict the study’s human trial outcomes. Good Ventures, Cari Tuna and Dustin Moskovitz’s foundation, has provided funding for the Washington University study. The foundation, with support from Open Philanthropy, has been investigating how best to fund scientific research that might help reduce the future burden of Alzheimer’s disease. Our scientific research team believes that Dr. Brubaker’s computational model, if successful, could improve drug discovery and reduce reliance on mouse experiments. This falls within our work on scientific research, specifically within our interest in advancing tools and techniques. Update (September 2023): Dr. Brubaker recently transferred to Case Western University, where he will continue his research. The remaining funds for this grant ($1,334,011) were transferred to Case Western.

Source evidence

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coefficientgiving.org/funds/Coefficient Giving resource

confirmed95%deterministic-row-match · 4/3/2026

Name: Purdue University — Preclinical Data Research (Douglas Brubaker)
Grantee: Purdue University
Focus Area: Scientific Innovation: Tools and Techniques
Amount: $1,500,000.00
Date: Augu

NoteDeterministic match: grantee, amount, date matched in source snapshot (2714 rows)

Case № I2hnMdQcu1Filed 4/3/2026Confidence 95%